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4018214

Availability: In stock

H-Glu-Gly-Arg-chloromethylketone trifluoroacetate salt

4018214

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4018214.0005 5 mg Request lead time  
CHF 368.00
CHF 342.24 (7%)
4018214.0025 25 mg Ships within 3-5 business days  
CHF 1,471.00
CHF 1,368.03 (7%)
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Details

GGACK (EGR-CMK), inhibitor of the u-plasminogen activator. Irreversible covalent inhibitor of human hepsin.
Catalog Number N-1325
One Letter Code EGR-CMK
Synonyms GGACK
Molecular Formula C₁₄H₂₅ClN₆O₅
Relative Molecular Mass 392.84
CAS Registry Number [65113-67-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords uPA inhibitor
Areas of Interest Cardiovascular System & Diseases
Hematology
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Bachem product citations

R.C.Duncan et al., Mol. Immunol., 49, 593 (2012)
P.V.Bozhkov et al., Proc. Natl. Acad. Sci. USA, 102, 14463 (2005)
P.V.Bozhkov et al., Proc. Natl. Acad. Sci. U.S.A., 102, 14463 (2005)
D.Mangnall et al., Comp. Hepatol., 3, 11 (2004)
T.Bedsted et al., Biochemistry, 42, 8143 (2003)
T.Bedsted et al., Biochemistry, 42, 8143 (2003)
R.Egelund et al., Eur. J. Biochem., 268, 673 (2001)
P.Fuentes-Prior et al., Nature, 404, 518 (2000)
K.Fischer et al., FEBS Lett., 438, 101 (1998)

Product citations

M.Tripathi et al., J. Biol. Chem., 283, 30576 (2008)
M.Kusch et al., Thromb. Haemost., 79, 778 (1998)
G.Spraggon et al., Structure, 3, 681 (1995)

4018214

Enzyme Substrates Inhibitors
u-Plasminogen Activator    
Hepsin    
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