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Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price
4018082.0500 500 mg Request lead time  
CHF 578.00
CHF 537.54 (7%)


Substrate for S-adenosyl-methionine (SAM)-dependent methyltransferases, which methylate the C-terminal S-farnesyl-cysteine residue of several guanine nucleotidebinding proteins (G proteins) which participate in signal transduction. These include the single subunit "small" G proteins such as the p21 ras-related proteins and the heterotrimeric G proteins such as retinal transducin. Thus, a rapid assay for studying this carboxyl methyltransferase activity has been developed. Interestingly, AFC was also shown to inhibit the methylation of the transducin γ-subunit and of Ras-related proteins.
Catalog Number M-1935
Synonyms AFC
Molecular Formula C₂₀H₃₃NO₃S
Relative Molecular Mass 367.55
CAS Registry Number 135304-07-3
Storage Conditions -20 ± 5 °C
Keywords Substrate for S-adenosylmethionine-dependent methyltransferase


Enzyme Substrates Inhibitors
Protein-S-Isoprenylcysteine O-Methyltransferase