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4018011

Availability: In stock

Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH₂ trifluoroacetate salt

4018011

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4018011.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 237.00
CHF 220.41 (7%)
4018011.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 946.00
CHF 879.78 (7%)

Details

The FRET peptide Dnp-PLGLWAr-amide is an efficient substrate for interstitial/vertebrate collagenase (MMP-1), stromelysin (MMP-3), and especially for the gelatinases (MMP-2 and MMP-9) and the punctuated metalloproteinase (MMP-7).
Catalog Number M-1855
APC Number 81-7-70
One Letter Code Dnp- PLGLWAR -NH₂
Synonyms MMP Substrate, Fluorogenic
Molecular Formula C₄₅H₆₄N₁₄O₁₁
Relative Molecular Mass 977.09
CAS Registry Number 121282-17-5
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Cancer Research
Inflammation Research
Links / Documents:

Bachem product citations

M.Lopez-Pelegrin et al., Angew. Chem. Int. Ed. Engl., 53, 10624 (2014)
M.Lopez-Pelegrin et al., Angew. Chem. Int. Ed. Engl., 53, 10624 (2014)
M.Lopez-Pelegrin et al., J. Biol. Chem., 288, 21279 (2013)
N.Philips et al., J. Cosmet. Sci., 61, 125 (2010)
S.Chowdhury et al., Mol. Ther., 9, 85 (2004)
H.I.Park et al., J. Biol. Chem., 277, 35168 (2002)
H.I.Park et al., J. Biol. Chem., 277, 35168 (2002)
F.Martin et al., J. Virol., 73, 6923 (1999)
F.Martin et al., J. Virol., 73, 6923 (1999)

Product citations

F.Martin et al., J. Virol., 73, 6923 (1999)
D.M.Bickett et al., Anal. Biochem., 212, 58 (1993)
C.G.Knight et al., FEBS Lett., 296, 263 (1992)
K.Darlak et al., J. Biol. Chem., 265, 5199 (1990)
M.S.Stack and R.D.Gray, J. Biol. Chem., 264, 4277 (1989)
Y.Masui et al., Biochem. Med., 17, 215 (1977)

4018011

Enzyme Substrates Inhibitors
Gelatinase B    
Interstitial Collagenase    
Matrilysin    
Stromelysin 1    
Gelatinase A    
Matrix Metalloproteinase-1 (MMP-1)    
Matrix Metalloproteinase-2 (MMP-2)    
Matrix Metalloproteinase-3 (MMP-3)    
Matrix Metalloproteinase-9 (MMP-9)    
Matrix Metalloproteinase-7 (MMP-7)