Ac-Tyr-Val-Ala-Asp-AMC 4017748 | Bachem https://shop.bachem.com/4017748.html

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Availability: In stock

Ac-Tyr-Val-Ala-Asp-AMC

4017748

Product No.	Pack Size	Available	ADS InfoAnalytical Data Sheet	List Price	Online Order Price	Qty
4017748.0005	5 mg	Ships within 1 business day	ADSExemplary Data Sheet of a current available lot.	CHF 168.00	CHF 156.24 (7%)
4017748.0025	25 mg	Ships within 1 business day	ADSExemplary Data Sheet of a current available lot.	CHF 672.00	CHF 624.96 (7%)

Details

Ac-YVAD-AMC is a fluorogenic substrate for caspase-1 (ICE). It displayed a Km of 8.5 ± 0.5 µM for recombinant human caspase-1.

Catalog Number I-1630

APC Number 81-7-30

One Letter Code Ac-YVAD-AMC

Synonyms Ac-YVAD-AMC

Molecular Formula C₃₃H₃₉N₅O₁₀

Relative Molecular Mass 665.70

CAS Registry Number 149231-65-2

Source Synthetic

Storage Conditions -20 ± 5 °C

Keywords ICE substrate

Application Apoptosis & Necrosis

Links / Documents:

Bachem product citations

Y.M.Cai et al., New Phytol., (2017)

I.M.Bugueno et al., PLoS One, 11, e0154590 (2016)

I.Julian et al., J. Exp. Bot., 64, 2929 (2013)

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M.Dewaele et al., Methods Mol. Biol., 635, 7 (2010)

G.Bianchi et al., Blood, 113, 3040 (2009)

R.He et al., J. Biol. Chem., 283, 774 (2008)

A.Hueber et al., Invest. Ophthalmol. Vis. Sci., 44, 2851 (2003)

T.Zuliani et al., Cytometry A, 54, 100 (2003)

D.Lee et al., J. Med. Chem., 44, 2015 (2001)

V.I.Rotari et al., Biol. Chem., 382, 953 (2001)

A.Khar et al., FEBS Lett., 445, 165 (1999)

I.Marzo et al., FEBS Lett., 427, 198 (1998)

R.V.Talanian et al., J. Biol. Chem., 271, 21853 (1996)

T.Fernandes-Alnemri et al., Cancer Res., 55, 6045 (1995)

Product citations

N.P.Walker et al., Cell, 78, 343 (1994)

N.A.Thornberry et al., Nature, 356, 768 (1992)

4017748

Enzyme	Substrates	Inhibitors
Caspase-1 (ICE)

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