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4017732

Availability: In stock

Z-Val-Lys-Met-AMC acetate salt

4017732

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4017732.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 315.00
CHF 292.95 (7%)

Details

The motif VKM corresponds to APP (669-671). Substrate for Amyloid A4-generating enzymes and cathepsin B. Hook et al. used Z-VKM-MCA to detect β-secretase activity in isolated chromaffin vesicles.
Catalog Number I-1625
Molecular Formula C₃₄H₄₅N₅O₇S
Relative Molecular Mass 667.83
CAS Registry Number 141223-71-4
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Alzheimer's Disease
Links / Documents:
Brochures:

Product citations

V.Hook et al., Biochim. Biophys. Acta, 1824, 89 (2012)
V.Y.H.Hook et al., J. Biol. Chem., 293, 7745 (2008)
V.Hook et al., Biol. Chem., 386, 931 (2005)
H.Matsui and T.Takahashi, Mol. Reprod. Dev., 62, 99 (2002)
V.Y.H.Hook et al., J. Neurochem., 81, 237 (2002)
H.Koike et al., J. Biochem., 126, 235 (1999)
S.Ishiura et al., Neurosci. Lett., 115, 329 (1990)

4017732

Enzyme Substrates Inhibitors
Cathepsin B