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Details
The 4-Nitro-Z (pNZ) group has gained interest as semipermanent Nε protecting group in combination with Fmoc/tBu/Aloc. It can be removed selectively with SnCl₂/HCl in DMF.
Lys(pNZ) is used as inactive control in studies using the DPP IV inhibitors H-Lys(4-nitro-Z)-pyrrolidide and H-Lys(4-nitro-Z)-thiazolidide.
Catalog Number
E-2960
Molecular Formula
C₁₄H₁₉N₃O₆
Relative Molecular Mass
325.32
CAS Registry Number
3557-90-2
Storage Conditions
RT
Links / Documents:
Bachem product citations
Product citations
A.Isidro-Llobet et al.,
Tetrahedron Lett.,
46,
7733 (2005)