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Details
The bioactive tetrapeptide goralatide which corresponds to the N-terminus of Thymosin β₄, is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP has been shown to reduce the damage to specific compartments in the bone marrow resulting from treatment with chemotherapeutic agents, ionizing radiations, hyperthermy, or phototherapy. It protects from doxorubicin-induced toxicity. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE).
Catalog Number
H-1156
APC Number
87-0-25
One Letter Code
Ac-SDKP
Synonyms
Thymosin β4 (1-4), AcSDKP, Goralatide, Stem Cell Proliferation Inhibitor
Molecular Formula
C₂₀H₃₃N₅O₉
Relative Molecular Mass
487.51
CAS Registry Number
127103-11-1
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Links / Documents:
Bachem product citations
Product citations
4016348
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Angiotensin I-Converting Enzyme (ACE) |
