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Details
Acetyl-pepstatin is reported to be an effective inhibitor of HIV-1 proteinase (Ki = 20 nM at pH 4.7) and of HIV-2 proteinase (Ki = 5 nM at pH 4.7). Ac-Val-Val-Sta-Ala-Sta also inhibits the P. falciparum aspartyl protease plasmepsin II, IC₅₀ 0.6 nM.
Catalog Number
N-1250
APC Number
84-0-01
Molecular Formula
C₃₁H₅₇N₅O₉
Relative Molecular Mass
643.82
CAS Registry Number
[28575-34-0]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Infectious Disease
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Brochures:
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Bachem product citations
4015928
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Cathepsin D | ||
| Chymosin | ||
| Pepsin A | ||
| Retropepsin | ||
| Plasmepsin II | ||
| HIV-2 Protease |
