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4012071

Availability: In stock

MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone

4012071

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4012071.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)
4012071.0100 100 mg Ships within 3-5 business days  
CHF 1,104.00
CHF 1,026.72 (7%)

Details

MeOSuc-AAPA-CMK, inhibitor of human neutrophil elastase. The structure of the enzyme-inhibitor complex at 1.84 Å resolution reveals crosslinking of the catalytic residues His-57 and Ser-195 by the peptidyl chloromethylketone.
Catalog Number N-1280
APC Number 81-4-66
Molecular Formula C₂₀H₃₁ClN₄O₇
Relative Molecular Mass 474.94
CAS Registry Number [111682-13-4]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Neutrophil elastase inhibitor
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Bachem product citations

D.Ivanov et al., J. Biol. Chem., 281, 17246 (2006)
D.Ivanov et al., J. Biol. Chem., 281, 17246 (2006)
B.Korkmaz et al., Am. J. Respir. Cell Mol. Biol., 30, 801 (2004)
L.Ottonello et al., J. Leukoc. Biol., 75, 99 (2004)

Product citations

M.A.Navia et al., Proc. Natl. Acad. Sci. USA, 86, 7 (1989)

4012071

Enzyme Substrates Inhibitors
Leukocyte Elastase