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Details
A major metabolite of L-DOPA. Elevated concentrations of 3-MT in body fluids are indicators for a variety of brain and carcinoid tumors. N-Acetylation of 3-MT yields NAMDA, which in vitro inhibits GTP cyclohydrolase I, the rate-limiting enzyme for tetrahydrobiopterin biosynthesis. NAMDA also reduces nitrite accumulation, an oxidative metabolite of NO, without directly inhibiting NOS activity.
CAS Number (net): 554-52-9.
Catalog Number
Q-1330
Synonyms
3-MT · HCl, 3-O-Methyldopamine · HCl
Molecular Formula
C₉H₁₃NO₂ · HCl
Relative Molecular Mass
203.67
CAS Registry Number
1477-68-5
EINECS Number
216-035-1
Storage Conditions
+5 ± 3 °C
Keywords
DOPA metabolite
Application
Cancer Research
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