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Suc-Leu-Leu-Val-Tyr-AMC

4011369

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
4011369.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 210.00
CHF 195.30 (7%)
4011369.0100 100 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 630.00
CHF 585.90 (7%)
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Details

The fluorogenic substrate Suc-LLVY-AMC is used for measuring the chymotrypsin-like activity of the 20S proteasome, in combination with e.g. Bz-VGR-AMC, I-1085 (for assaying its trypsin-like activity) and Z-LLE-AMC, I-1945 (for determining its PGPH activity).
Suc-LLVY-AMC is also cleaved by a chymotrypsin-like enzyme from sperm extract of the ascidian Halocynthia roretzi, a strong inhibitor of fertilization. The substrate has also been used to analyze the chymotrypsin-like activity of trypsins as well as chymase from rat mast cells. Furthermore, Suc-LLVY-AMC is a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain.
Catalog Number I-1395
APC Number 81-1-07
One Letter Code Suc-LLVY-AMC
Synonyms Chymotrypsin Substrate III, Fluorogenic
Molecular Formula C₄₀H₅₃N₅O₁₀
Relative Molecular Mass 763.89
CAS Registry Number [94367-21-2]
Source Synthetic
Storage Conditions -20 ± 5 °C

Bachem product citations

T.-L.Chang et al., Journal of Functional Foods, 17, 857 (2015)
F.Gonzalez, Nat. Prod. Chem. Res., 2, (2014)
N.Basse et al., Comptes Rendus Chimie, 12, 1163 (2009)

4011369

Enzyme Substrates Inhibitors
Chymase    
Papain    
Multicatalytic Endopeptidase Complex    
Calpain    
Carboxypeptidase C    
Calpain-2    
Envelysin    
Proteasome Endopeptidase Complex    
Kexin