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Details
zHFFe, a good substrate for pepsin.
Hertel et al identified zHFFe as a potent inhibitor of zero-trans glucose flux with a Ki of 26 μM. Similar to HIV protease inhibitors, transport inhibition by this peptide was acute, non-competitive, and reversible. Within a Xenopus oocyte expression system, zHFFe acutely and reversibly inhibited GLUT4-mediated glucose uptake, whereas GLUT1 activity was unaffected at concentrations as high as 1 mM.
Catalog Number
M-1270
One Letter Code
Z- HFF -OEt
Molecular Formula
C₃₄H₃₇N₅O₆
Relative Molecular Mass
611.70
CAS Registry Number
13053-61-7
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Links / Documents:
Bachem product citations
4011308
Enzyme | Substrates | Inhibitors |
---|---|---|
Pepsin A |