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Details
S-protected derivative for the introduction of a deamino-penicillamine residue. Building block for the preparation of oxytocin and vasopressin antagonists. Peptide thioesters for chemical ligation may be obtained by Fmoc-SPPS using a deaminopenicillamine-derived linker, as premature cleavage during Fmoc removal is inhibited by steric hindrance. Tegge et al. developed a deaminopenicillamine-based disulfide linker for the Fmoc-SPPS of cyclic Cys-containing peptides.
Catalog Number
Q-1610
Synonyms
S-(4-Methoxybenzyl)-deamino-penicillamine
Molecular Formula
C₁₃H₁₈O₃S
Relative Molecular Mass
254.35
CAS Registry Number
[268219-99-4]
Storage Conditions
+5 ± 3 °C
Links / Documents:
Product citations
X.Li et al.,
Tetrahedron Lett.,
39,
8669 (1998)
