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Details
The tetrapeptide DAHK corresponding to the N-terminal sequence of human serum albumin forms a tight binding site for Cu(II) ions. DAHK inhibits Cu(II)-induced oxidative DNA double strand breaks. The tetrapeptide is as effective as HSA in preventing neuronal death induced by CuCl₂/ascorbic acid. DAHK may be an effective, small-molecular-weight alternative to HSA as a therapeutic agent for stroke.
Catalog Number
H-2020
One Letter Code
DAHK
Molecular Formula
C₁₉H₃₁N₇O₇
Relative Molecular Mass
469.50
CAS Registry Number
[111543-77-2]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Copper-binding motif of human serum albumin
Areas of Interest
Apoptosis & Necrosis
Cardiovascular System & Diseases
Cardiovascular System & Diseases
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