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Details
Catalyst for asymmetric cyanohydrin synthesis. The addition of hydrogen cyanide to benzaldehyde gives the highest optical yield ever obtained for the corresponding cyanohydrin.
In a study of McCleland et al., Cyclo(His-Phe) showed significant anti-tumour activity, causing reduction of cell viability in cervical cancer cells. In isolated rat hearts, the diketopiperazine caused a gradual reduction of heart rate and a decrease in coronary flow rate.
Catalog Number
G-1740
Molecular Formula
C₁₅H₁₆N₄O₂
Relative Molecular Mass
284.32
CAS Registry Number
56586-95-9
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Chiral catalyst; Anti-tumor cyclopeptide
Application
Cancer Research
Links / Documents:
Bachem product citations
Product citations
M.B.Martins and I.Carvalho,
Tetrahedron,
63,
9923 (2007)
K.Tanaka et al.,
J. Org. Chem.,
55,
181 (1990)
J.I.Oku and S.Inoue,
J. Chem. Soc. Chem. Commun.,
(1981)
