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Details
The BSi (or TBDMS) ether is somewhat more labile towards TFA than the tBu ether protection of the Ser hydroxyl moiety. Ser(TBDMS) can be cleaaved selectiviely in the presence of Boc/tBu with Bu₄N fluoride in DMF, but Fmoc is removed under these conditions as well.
Catalog Number
B-1225
Synonyms
Fmoc-Ser(TBDMS)-OH
Molecular Formula
C₂₄H₃₁NO₅Si
Relative Molecular Mass
441.60
CAS Registry Number
146346-81-8
Storage Conditions
-20 ± 5 °C
Links / Documents:
Product citations
P.M.Fischer,
Tetrahedron Lett.,
33,
7605 (1992)