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Details
Reagent for the introduction of the Fmoc-amino-protecting group, which is stable towards acids and catalytic hydrogenation but is readily cleaved under mildly basic non-hydrolytic conditions. The use of this reagent in the protection of hydroxy groups and amino groups in nucleotides has been reported as well.
Fmoc-chloride is often used for pre-column derivatization of amines and amino acids in analytical HPLC.
Catalog Number
Q-1235
Synonyms
Fmoc-chloride
Molecular Formula
C₁₅H₁₁ClO₂
Relative Molecular Mass
258.70
CAS Registry Number
28920-43-6
EINECS Number
249-313-6
Storage Conditions
-20 ± 5 °C
Links / Documents:
Bachem product citations
Product citations
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1657 (1989)
L.A.Carpino et al.,
Acc. Chem. Res.,
20,
401 (1987)
S.Einarsson et al.,
Anal. Chem.,
58,
1638 (1986)