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Details
Reagent for the introduction of the Fmoc-amino-protecting group, which is stable towards acids and catalytic hydrogenation but is readily cleaved under mildly basic non-hydrolytic conditions. The use of this reagent in the protection of hydroxy groups and amino groups in nucleotides has been reported as well.
Fmoc-chloride is often used for pre-column derivatization of amines and amino acids in analytical HPLC.
Catalog Number
Q-1235
Synonyms
Fmoc-chloride
Molecular Formula
C₁₅H₁₁ClO₂
Relative Molecular Mass
258.70
CAS Registry Number
28920-43-6
EINECS Number
249-313-6
Storage Conditions
-20 ± 5 °C
Links / Documents:
Bachem product citations
Product citations
R.J.Vreeken et al.,
J. Chromatogr. A,
794,
187 (1998)
U.Büttikofer et al.,
Chromatographia,
31,
441 (1991)
L.H.Koole et al.,
J. Org. Chem.,
54,
1657 (1989)
L.A.Carpino et al.,
Acc. Chem. Res.,
20,
401 (1987)
S.Einarsson et al.,
Anal. Chem.,
58,
1638 (1986)
