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4003801

Availability: In stock

Z-Phe-Ala-diazomethylketone

4003801

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4003801.0050 50 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 368.00
CHF 342.24 (7%)

Details

Z-FA-CHN2, a specific inhibitor of thiol proteinases, e.g. cathepsin B. The diazomethyl ketones Z-FA-CHN2 and Z-LVG-CHN2 inhibited cathepsin L-like cysteine proteinase B from Leishmania mexicana.
Catalog Number N-1040
One Letter Code Z-FA-DMK
Molecular Formula C₂₁H₂₂N₄O₄
Relative Molecular Mass 394.43
CAS Registry Number 71732-53-1
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Cysteine proteinase inhibitor
Links / Documents:

Bachem product citations

B.T.Roux et al., Sci. Rep., 7, 12389 (2017)
I.Lauritzen et al., Acta Neuropathol., 132, 257 (2016)
J.K.Morelli and P.J.Ciaccio, J. Toxicol., 2013, 956404 (2013)
M.W.Robinson et al., PLoS Negl. Trop. Dis., 5, e1012 (2012)
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N.Nowak et al., J. Biol. Chem., 279, 38260 (2004)
N.J.Nkemgu et al., Int. J. Antimicrob. Agents, 22, 155 (2003)
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X.Bi et al., Proc. Natl. Acad. Sci. USA, 98, 8832 (2001)
A.J.Nisbet and P.F.Billingsley, Int. J. Parasitol., 30, 19 (2000)
J.W.Irvine et al., FEMS Microbiol. Lett., 149, 45 (1997)
C.D.Robertson et al., J. Gen. Microbiol., 136, 921 (1990)

Product citations

N.Nowak et al., J. Biol. Chem., 279, 38260 (2004)
X.Bi et al., Proc. Natl. Acad. Sci. USA, 98, 8832 (2001)
M.J.Frame et al., Parasitology, 121, 367 (2000)
J.M.Richardson et al., J. Cell Biol., 107, 2097 (1988)
G.D.J.Green and E.Shaw, J. Biol. Chem., 256, 1923 (1981)
E.Shaw and R.T.Dean, Biochem. J., 186, 385 (1980)

4003801

Enzyme Substrates Inhibitors
Cathepsin B    
Cathepsin H    
Cathepsin L    
Cathepsin S    
Histolysain