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4002941

Availability: In stock

Z-Gly-Gly-Leu-pNA

4002941

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4002941.1000 1 g Ships within 3-5 business days  
CHF 630.00
CHF 585.90 (7%)

Details

The chromogenic substrate Z-GGL-pNA is used alone or in combination with other substrates as Suc-LLVY-AMC for measuring the chymotrypsin-like activity of the proteasome. Z-GGL-pNA is also cleaved by proteinase yscE (kexin), subtilisins, and neutral endopeptidase 24.5.
Catalog Number L-1230
One Letter Code Z-GGL-pNA
Molecular Formula C₂₄H₂₉N₅O₇
Relative Molecular Mass 499.52
CAS Registry Number 53046-98-3
Source Synthetic
Storage Conditions -20 ± 5 °C
Links / Documents:

Bachem product citations

M.Gogliettino et al., FEBS J., 281, 401 (2014)
M.Gogliettino et al., PLoS One, 7, e37921 (2012)
Z.Li et al., Biochem. Biophys. Res. Commun., 319, 1171 (2004)
Z.Li et al., J. Neurochem., 90, 19 (2004)

Product citations

J.Yang et al., J. Neuroimmunol., 181, 34 (2006)
S.Wilk and W.E.Chen, Curr. Protoc. Protein Sci., 21, Unit 21 6 (2001)
M.E.Figueiredo-Pereira et al., J. Biol. Chem., 271, 16455 (1996)
W.Heinemeyer et al., EMBO J., 10, 555 (1991)
R.Zolfaghari et al., Biochem. J., 241, 129 (1987)
Y.Kanaoka et al., Chem. Pharm. Bull., 33, 1721 (1985)
O.Emter and D.H.Wolf, FEBS Lett., 166, 321 (1984)
T.Achstetter et al., J. Biol. Chem., 259, 13344 (1984)
V.M.Stepanov et al., Biochem. Biophys. Res. Commun., 77, 298 (1977)
L.A.Lyublinskaya et al., Anal. Biochem., 62, 371 (1974)

4002941

Enzyme Substrates Inhibitors
Kexin    
Proteasome Endopeptidase Complex    
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