Return to Previous Page
Details
Angiotensin I, DRVYIHPFHL, is cleaved by angiotensin-converting enzyme (ACE) yielding Ang II and the dipeptide His-Leu. Ang I is also converted to Ang II by chymase, especially in the human heart. Hence, this mast cell protease is also involved in blood pressure regulation. The chymase pathway gains importance in inflammatory conditions.
Catalog Number
H-1680
APC Number
12-1-10
One Letter Code
DRVYIHPFHL
Synonyms
Ang I, Angiotensinogen (1-10), Angiotensin I, human
Molecular Formula
C₆₂H₈₉N₁₇O₁₄
Relative Molecular Mass
1296.50
CAS Registry Number
484-42-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Cardiovascular System & Diseases
Links / Documents:
Bachem product citations
V.Dorcak et al.,
Electrochemistry Communications,
31,
80 (2013)
A.Picon et al.,
Int. Dairy J.,
20,
156 (2010)
N.Le Yondre et al.,
Open Proteomics J.,
1,
99 (2008)
C.-F.Huang et al.,
Journal of Polymer Research,
12,
449 (2005)
K.Kotaro Satoh et al.,
Macromolecules,
33,
5405 (2000)
K.Satoh et al.,
Macromolecules,
33,
5830 (2000)
4002346
Enzyme | Substrates | Inhibitors |
---|---|---|
Dipeptidyl-Peptidase III (DPP III) | ||
Neurolysin |