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Details
A readily soluble, specific and sensitive substrate for chymotrypsin and human pancreatic elastase. It is also hydrolyzed by cathepsin G and chymase. Furthermore it is the standard substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases). Thus, Suc-AAPF-pNA has been used for an uncoupled protease-free assay of PPIase activity.
Catalog Number
L-1400
One Letter Code
Suc-AAPF-pNA
Synonyms
SAAPNA
Molecular Formula
C₃₀H₃₆N₆O₉
Relative Molecular Mass
624.65
CAS Registry Number
70967-97-4
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Application
Gastrointestinal Research
Links / Documents:
Bachem product citations
L.González et al.,
Am. J. Anal. Chem.,
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Enz. Mic. Tech.,
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A.Vercet et al.,
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A.Vercet et al.,
Innovative Food Science & Emerging Technologies.,
2,
139 (2001)
Product citations
J.K.A.Kamal et al.,
Chem. Phys. Lett.,
387,
209 (2004)
G.Fischer,
Angew. Chem. Int. Ed. Engl.,
33,
1415 (1994)
4002299
Enzyme | Substrates | Inhibitors |
---|---|---|
Cathepsin G | ||
Chymotrypsin | ||
Pancreatic Elastase | ||
Chymase | ||
Brachyurin | ||
Peptidylprolyl Isomerase |