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4001034

Availability: In stock

H-Glu(H-Lys-OH)-OH

4001034

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4001034.0250 250 mg Ships within 3-5 business days  
CHF 105.00
CHF 97.65 (7%)
4001034.1000 1 g Ships within 3-5 business days  
CHF 315.00
CHF 292.95 (7%)

Details

The Glu-Lys isopeptide bond is formed as a crosslink in proteins in normal, not virus-transformed cells. Additionally, the acceleration of fibrin ε-(γ-glutamyl)lysine (GGEL) crosslinking by red blood cells has been observed. GGEL detected in the CSF is a biomarker of neurodegenerative diseases.
Catalog Number G-1970
Synonyms H-γ-Glu-ε-Lys-OH, H-Lys(retro-HO-Glu-H)-OH
Molecular Formula C₁₁H₂₁N₃O₅
Relative Molecular Mass 275.31
CAS Registry Number 17105-15-6
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Alzheimer's Disease
Di- and Tripeptides
Links / Documents:

Bachem product citations

M.de Jager et al., Neurobiol. Aging, 34, 1159 (2013)
A.J.Oakley et al., J. Biol. Chem., 285, 9642 (2010)
C.Schafer et al., J. Agric. Food Chem., 53, 2830 (2005)
T.S.Johnson et al., J. Am. Soc. Nephrol., 14, 2052 (2003)
E.Schmitt et al., Cell Death Differ., 5, 506 (1998)

Product citations

W.Bains, Rejuvenation Res., 16, 495 (2013)
T.Jeitner et al., J. Neurochem., 79, 1109 (2001)
Z.Nemes et al., Neurobiol. Aging, 22, 403 (2001)
E.Tarcsa and L.Fesus, Anal. Biochem., 186, 135 (1990)
E.W.Ferguson and G.E.Sander, Nature, 278, 183 (1979)
P.J.Birckbichler et al., Biochem. Biophys. Res. Commun., 84, 232 (1978)