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4000937

Availability: In stock

H-Lys-Trp-Lys-OH acetate salt

4000937

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4000937.0250 250 mg Ships within 3-5 business days  
CHF 252.00
CHF 234.36 (7%)

Details

A peptide with binding properties to various single-stranded copolymers of adenine, cytosine and to DNA. The tripeptide KWK recognizes and cleaves DNA at apurinic sites. See also H-Lys-Tyr-Lys-OH. Prata et al. used C-terminally lipidated KWK for gene delivery.
Catalog Number H-4265
One Letter Code KWK
Molecular Formula C₂₃H₃₆N₆O₄
Relative Molecular Mass 460.58
CAS Registry Number 38579-27-0
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Di- and Tripeptides
Links / Documents:

Bachem product citations

E.Watanabe et al., Magn. Reson. Chem., 48, 205 (2010)
V.Colot et al., FEBS Lett., 169, 205 (1984)

Product citations

C.A.H.Prata et al., Bioconjugate J., 19, 418 (2008)
A.Laigle and C.Lacombe, Stud. Biophys., 89, 11 (1982)
N.J.Duker and D.M.Hart, Biochem. Biophys. Res. Commun., 105, 1433 (1982)
T.A.Cha and A.H.Maki, Biochemistry, 21, 6586 (1982)
J.Pierre and J.Laval, J. Biol. Chem., 256, 10217 (1981)
T.Behmoaras et al., Proc. Natl. Acad. Sci. USA, 78, 926 (1981)
T.Behmoaras et al., Nature, 292, 858 (1981)
T.Montenay-Garestier et al., Biochimie, 63, 937 (1981)
A.G.Szabo and D.M.Rayner, Biochem. Biophys. Res. Commun., 94, 909 (1980)
F.Toulme et al., Biochemistry, 19, 870 (1980)
J.C.Maurizot et al., Biochemistry, 17, 2096 (1978)