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Educt for the γ-modification of glutamic acid, e.g. for obtaining the 1- and 2-adamantyl ester, acid-labile γ-carboxyl protecting groups. Feichtinger et al. obtained δ,ω,ω'-protected arginine from Z-Glu-OBzl via reduction to the alcohol followed by guanidinylation under Mitsunobu conditions. Additionally, Z-Glu-OBzl has been used as highly effective acyl donor in enzymatic peptide synthesis.
Catalog Number
C-1570
Molecular Formula
C₂₀H₂₁NO₆
Relative Molecular Mass
371.39
CAS Registry Number
[3705-42-8]
Storage Conditions
RT
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Bachem product citations
Product citations
K.Feichtinger et al.,
J. Org. Chem.,
63,
8432 (1998)
Y.Okada and Y.Mu,
Chem. Pharm. Bull.,
45,
88 (1997)
V.Rolland-Fulcrand et al.,
Catal. Lett.,
27,
235 (1994)
