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Details
Leu-OMe (LME) causes lysosomal disruption and death of human monocytes (M phi). In addition, LME removed natural killer cell (NK) activity from human peripheral mononuclear cells (PBM). During incubation of human lymphocytes with Leu-OMe, the dipeptide Leu-Leu-OMe (G-2550) which is responsible for the NK-toxicity, is formed.
Catalog Number
E-2080
Molecular Formula
C₇H₁₅NO₂ · HCl
Relative Molecular Mass
181.66
CAS Registry Number
[7517-19-3]
EINECS Number
231-375-0
Storage Conditions
+5 ± 3 °C
Areas of Interest
Immunomodulating Agents
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