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4000599

Availability: In stock

Z-Phe-His-Leu-OH

4000599

Product No. Pack Size Available ADS InfoAnalytical Data Sheet List Price Online Order Price Qty
4000599.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 189.00
CHF 175.77 (7%)
4000599.1000 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 567.00
CHF 527.31 (7%)

Details

Substrate for angiotensin I-converting enzyme. Cleavage of Z-FHL by ACE yields His-Leu (G-2310), which can be quantified by generating a fluorescent adduct with o-phthalaldehyde.
Catalog Number M-1305
One Letter Code Z- FHL
Molecular Formula C₂₉H₃₅N₅O₆
Relative Molecular Mass 549.63
CAS Registry Number 28458-19-7
Source Synthetic
Storage Conditions -20 ± 5 °C
Application Cardiovascular System & Diseases
Links / Documents:

Bachem product citations

C.J.Yates et al., J. Biol. Chem., 289, 1798 (2014)
M.P.Ocaranza et al., J. Hypertens., 32, 771 (2014)
L.C.Maluf-Meiken et al., Int. J. Hypertens., 2012, 581780 (2012)
J.C.Perry et al., Auton. Neurosci., 160, 32 (2011)
C.S.Anthony et al., J. Biol. Chem., 285, 35685 (2010)
P.Le Corvoisier et al., Eur. J. Heart Fail., 12, 1171 (2010)
S.M.Danilov et al., J. Cardiovasc. Pharmacol., 52, 90 (2008)
I.V.Balyasnikova et al., J. Proteome Res., 6, 1580 (2007)
M.P.Ocaranza et al., Life Sci., 78, 1535 (2006)
M.P.Ocaranza et al., Hypertension, 48, 572 (2006)
O.E.Skirgello et al., Biochemistry, 45, 4831 (2006)
I.V.Balyasnikova et al., J. Proteome Res., 4, 258 (2005)
J.E.Jalil et al., Hypertension, 46, 1362 (2005)
J.E.Jalil et al., J. Hum. Hypertens., 18, 119 (2004)

Product citations

C.Welsch et al., J. Cardiovasc. Pharmacol., 14 (Suppl.4), S26 (1989)
H.Schweisfurth and S.Schiöberg-Schiegnitz, Enzyme, 32, 12 (1984)
J.Friedland and E.Silverstein, Am. J. Clin. Pathol., 66, 416 (1976)
Y.Piquilloud et al., Biochim. Biophys. Acta, 206, 136 (1970)
M.Roth et al., Experientia, 25, 1247 (1969)

4000599

Enzyme Substrates Inhibitors
Peptidyl-Dipeptidase A    
Angiotensin I-Converting Enzyme (ACE)    
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