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Availability: In stock

DEPBT
3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one

Q-2565

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
Q-2565.0025 25 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 252.00
CHF 234.36 (7%)
Q-2565.0100 100 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 757.00
CHF 704.01 (7%)
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Details

DEPBT, a crystalline phosphonium-type coupling reagent, mediates amide bond formation with a remarkable resistance to racemization. Thus, DEPBT is an excellent activation reagent for coupling the racemization-prone Fmoc-His(Trt)-OH. The use of DEPBT permitted the total synthesis of the antiviral peptide antibiotic feglymycin, which contains a high proportion of ring-substituted phenylglycines.
Item Number 4029249
Molecular Formula C₁₁H₁₄N₃O₅P
Relative Molecular Mass 299.22
CAS Registry Number [165534-43-0]
Storage Conditions -20 ± 5 °C

Product citations

M.Mergler et al., Innovation and Perspectives in Solid Phase Synthesis and Combinatorial Libraries, 7th International Symposium, Southampton, p. 235, R.Epton, ed., Mayflower Worldwide, (2002)
C.-X.Fan et al., Synth. Commun., 26, 1455 (1996)