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Caspase-3 Precursor Protease Inhibitors

The apoptotic cysteine protease, caspase-3, is expressed in cells as an inactive 32 kD precursor from which 17 kD (p17) and 12 kD (p12) subunits of the mature caspase-3 were proteolytically generated during apoptosis. Using a cell-free caspase-3 processing assay it has been demonstrated, that the caspase-3 precursor appears to be cleaved first between Asp¹⁷⁵ and Ser¹⁷⁶, producing the p12 and p20 subunits. Subsequently, the p20 was cleaved between Asp²⁸ and Ser²⁹, generating the mature p17 subunit.
  • Name
  1. N-1625.0005 5 mg
    €158.00
    N-1625.0025 25 mg
    €634.00
  2. N-1620.0005 5 mg
    €158.00
    N-1620.0025 25 mg
    €634.00