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Details
Cell permeable caspase-8 inhibitor. The O-methyl groups serve to enhance the cell membrane permeability. Within the cell this inhibitor is converted to its biological active form Z-LETD-FMK by endogenous esterases which hydrolyze the O-methyl groups.
Item Number
4042558
Synonyms
Z-LE(OMe)TD(OMe)-FMK
Molecular Formula
C₃₀H₄₃FN₄O₁₁
Relative Molecular Mass
654.69
CAS Registry Number
[1926163-60-1]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Cell permeable caspase-8 inhibitor
Areas of Interest
Apoptosis & Necrosis
Links / Documents:
Brochures:
Bachem product citations
N-1975
Enzyme | Substrates | Inhibitors |
---|---|---|
Caspase-8 (MACH; FLICE; Mch5) |