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Availability: In stock

Fluorescein-6-carbonyl-Val-Ala-DL-Asp(OMe)-fluoromethylketone

N-1915

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1915.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 577.00
CHF 536.61 (7%)
N-1915.1000 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'030.00
CHF 957.90 (7%)
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Details

Fluorescently labeled VAD(OMe)-FMK is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspases in living cells and induces an arrest of further progress of apoptotic cell death. Thus, Fluorescein-6-carbonyl-Val-Ala-DL-Asp(OMe)-fluoromethylketone (the methyl ester of 6-FAM-VAD-FMK) allows to determine the amount of cells present in different stages of the apoptotic cascade and to calculate cell death kinetics. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy.
Item Number 4045853
One Letter Code 6-FAM-VAD(OMe)-FMK
Synonyms 6-FAM-VAD(OMe)-FMK
Molecular Formula C₃₅H₃₄FN₃O₁₁
Relative Molecular Mass 691.67
CAS Registry Number [560094-66-8]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE inhibitor
Areas of Interest Apoptosis & Necrosis

N-1915

Enzyme Substrates Inhibitors
Caspase-1 (ICE)