Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: In stock

Z-Ile-Leu-aldehyde

N-1895

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1895.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 206.00
CHF 191.58 (7%)
N-1895.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 824.00
CHF 766.32 (7%)
Add to Wish List
Add to Compare

Details

Z-IL-CHO, a cell-permeable, reversible inhibitor, reduces amyloid β (Aβ)-production by blocking γ-secretase activity in vitro (Aβ₄₀ IC₅₀ = 7.9 µM; Aβ₄₂ IC₅₀ = 7.6 µM). Besides blocking the formation of Aβ the dipeptide aldehyde Z-IL-CHO also blocks the production of the γ-CTF (γ-secretase-generated carboxyl-terminal fragment), but does not affect the formation of amyloid-β-precursor protein (APP).
Item Number 4048245
Molecular Formula C₂₀H₃₀N₂O₄
Relative Molecular Mass 362.47
CAS Registry Number [161710-10-7]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease

N-1895

Enzyme Substrates Inhibitors
γ-Secretase