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Availability: In stock

3,5-Difluorophenylacetyl-Ala-Phg-OMe

N-1890

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1890.0005 5 mg Ships within 3-5 business days  
CHF 155.00
CHF 144.15 (7%)
N-1890.0025 25 mg Ships within 3-5 business days  
CHF 618.00
CHF 574.74 (7%)
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Details

DAPM, a cell-permeable γ-secretase inhibitor with anti-aggregation properties that dose-dependently inhibits amyloid β-protein (Aβ) secretion in 7PA2 Chinese hamster ovary (CHO) cells with an half-maximal inhibitory concentration of IC₅₀ ~ 10 nM. DAPM prevents oligomer formation by selectively blocking the Aβ dimer and trimer formation at doses that allow appreciable monomer production.
Item Number 4047620
Synonyms DAPM
Molecular Formula C₂₀H₂₀F₂N₂O₄
Relative Molecular Mass 390.39
CAS Registry Number [208255-51-0]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease

N-1890

Enzyme Substrates Inhibitors
γ-Secretase