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Availability: In stock

H-Glu-Leu-Asp-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]-Ala-Glu-Phe-OH

N-1825

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1825.0500 0.5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 567.00
CHF 527.31 (7%)
N-1825.1000 1 mg Ships within 3-5 business days  
CHF 979.00
CHF 910.47 (7%)
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Details

Glu-Leu-Asp-Leu-psi[CHOH-CH₂]-Ala-Ala-Glu-Phe (ELDL-psi[CHOH-CH₂]-AAEF), a potent inhibitor for human brain memapsin-2 (β-secretase) with a Ki-value of 0.3 nM. The hydroxyethylene isostere of the Leu-Ala motif functions as a mimic of the transition state.
Item Number 4041643
Molecular Formula C₄₂H₆₅N₇O₁₅
Relative Molecular Mass 908.02
CAS Registry Number [1349991-28-1]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease

N-1825

Enzyme Substrates Inhibitors
β-Secretase