Return to Previous Page
Details
The peptide aldehyde Ac-IETD-CHO corresponds to one of the cleavage sites of the inactive 32 kD caspase-3 precursor (amino acids 172-175). In a concentration range of 0.5 µM, Ac-IETD-CHO.blocked the formation of the p17 subunit and concomitantly induced the accumulation of the 32 kD precursor.
Item Number
4027874
APC Number
81-3-00
One Letter Code
Ac-IETD-CHO
Synonyms
Ac-IETD-CHO
Molecular Formula
C₂₁H₃₄N₄O₁₀
Relative Molecular Mass
502.52
CAS Registry Number
[191338-86-0]
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Keywords
Caspase-8 inhibitor
Areas of Interest
Apoptosis & Necrosis
Links / Documents:
Brochures:
Bachem product citations
N-1620
| Enzyme | Substrates | Inhibitors |
|---|---|---|
| Caspase 3 Precursor Protease (Pro-CPP-32; Pro-Yama; Pro-Apopain) | ||
| Caspase-8 (MACH; FLICE; Mch5) | ||
| Granzyme B |
