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Availability: In stock

Z-Phe-Tyr-aldehyde

N-1540

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1540.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 189.00
CHF 175.77 (7%)
N-1540.0100 100 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 567.00
CHF 527.31 (7%)
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Details

Z-Phe-Tyrosinal is a potent and selective cathepsin L inhibitor. In the pit formation assay with unfractionated rat bone cells, 1.5 nM of Z-FY-CHO markedly inhibited parathyroid hormone-stimulated osteoclastic bone resorption. In ovariectomized mice, it suppressed at 2.5-10 mg/kg/day ip for four weeks bone weight loss dose-dependently.
Item Number 4027130
APC Number 32-5-02
Synonyms Z-FY-CHO, Cathepsin-L Inhibitor
Molecular Formula C₂₆H₂₆N₂O₅
Relative Molecular Mass 446.50
CAS Registry Number [167498-29-5]
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Cathepsin L inhibitor
Areas of Interest Osteoporosis Research

N-1540

Enzyme Substrates Inhibitors
Cathepsin B    
Cathepsin L    
Calpain