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Availability: In stock

Decanoyl-Arg-Val-Lys-Arg-chloromethylketone trifluoroacetate salt

N-1505

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1505.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 721.00
CHF 670.53 (7%)
N-1505.0025 25 mg Ships within 3-5 business days  
CHF 2'884.00
CHF 2'682.12 (7%)
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Details

Dec-RVKR-CMK binds to the catalytic site of furin and therefore acts as a potent inhibitor of cleavage and fusion activity of viral glycoproteins, as well as virus replication. Furthermore it was demonstrated that Dec-RVKR-CMK decreased the production of β-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Apart from furin, N-1505 also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).
Item Number 4026850
APC Number 13-1-11
Synonyms Furin Inhibitor I, Dec-RVKR-CMK, Furin Convertase Inhibitor (Chloromethylketone)
Molecular Formula C₃₄H₆₆ClN₁₁O₅
Relative Molecular Mass 744.42
CAS Registry Number [150113-99-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Furin inhibitor
Areas of Interest Virology

Bachem product citations

N-1505

Enzyme Substrates Inhibitors
Furin    
Kexin    
Matrix Metalloproteinase-2 (MMP-2)    
Site-1 Protease    
Flavivirin