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Availability: In stock

Boc-Asp(OBzl)-chloromethylketone

N-1430

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1430.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 721.00
CHF 670.53 (7%)
N-1430.1000 1 g Ships within 3-5 business days  
CHF 2'163.00
CHF 2'011.59 (7%)
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Details

Boc-Asp(OBzl)-CMK penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, this inhibitor reduces caspase-1-mediated processing of mature interleukin-1β in a monocytic cell line by 85 % without affecting tumor necrosis factor processing.
Item Number 4025953
APC Number 81-7-87
Synonyms Boc-Asp(OBzl)-CMK
Molecular Formula C₁₇H₂₂ClNO₅
Relative Molecular Mass 355.82
CAS Registry Number [172702-58-8]
Storage Conditions -20 ± 5 °C
Keywords ICE inhibitor

N-1430

Enzyme Substrates Inhibitors
Caspase-1 (ICE)