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Availability: In stock

Z-Asp(OtBu)-bromomethylketone

N-1425

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1425.0250 250 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 268.00
CHF 249.24 (7%)
N-1425.1000 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 803.00
CHF 746.79 (7%)
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Details

Intermediate for the synthesis of IL-1β converting enzyme (ICE, caspase-1) inhibitors or other inhibitors containing a C-terminal aspartyl residue modified by different methylketone derivatives. According to Németh el al., who detected an antiapoptotic activity for the compound itself, it may be used for studying the early events of apoptosis in some cell types.
Item Number 4026186
Molecular Formula C₁₇H₂₂BrNO₅
Relative Molecular Mass 400.27
CAS Registry Number [153088-76-7]
Storage Conditions -20 ± 5 °C
Keywords ICE inhibitor
Areas of Interest Apoptosis & Necrosis

Product citations

K.Németh et al., Int. J. Immunopharmacol., 19, 215 (1997)