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Availability: In stock

4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt

N-1405

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
N-1405.0005 5 mg Ships within 3-5 business days  
CHF 93.00
CHF 86.49 (7%)
N-1405.0025 25 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 371.00
CHF 345.03 (7%)
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Details

The water-soluble peptidylhydroxamic acid FN439 is a broad-spectrum inhibitor of human matrix metalloproteinases. 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH retains its activity even after prolonged incubation with pronase or human granulocyte elastase. FN 439 inhibits interstitial and granulocyte collagenases, granulocyte gelatinase and skin fibroblast stromelysin with IC₅₀ of 1 · 10⁻⁶ M, 3 · 10⁻⁵ M and 1.5 · 10⁻⁴ M, respectively.
Item Number 4025806
APC Number 76-4-75
One Letter Code PABA-GPla-NHOH
Synonyms FN-439, MMP Inhibitor 1
Molecular Formula C₂₃H₃₄N₆O₆
Relative Molecular Mass 490.56
CAS Registry Number [124168-73-6] net
Source Synthetic
Storage Conditions -20 ± 5 °C

N-1405

Enzyme Substrates Inhibitors
Gelatinase A    
Interstitial Collagenase    
Stromelysin 1    
Matrix Metalloproteinase-1 (MMP-1)