Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: In stock

(H-Asp-Glu-Val-Asp)₂-Rhodamine 110 trifluoroacetate salt

M-2620

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2620.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 185.00
CHF 172.05 (7%)
M-2620.0025 25 mg Request lead time  
CHF 742.00
CHF 690.06 (7%)
Add to Wish List
Add to Compare

Details

(DEVD)₂-R110, non-fluorescent peptidyl (DEVD)-Rhodamine 110-bisamide, is a highly sensitive, photostable fluorogenic substrate for the determination of caspase-3 activity. Characteristic for substrates based on Rhodamine 110 (R110) is that they contain two identical amino acids or peptides attached to a single fluorophor thereby suppressing its visible absorption and its fluorescence. Upon enzymatic cleavage, this substrate is converted first to the fluorescent monoamide and then to the even more fluorescent R110. The spectral properties of these hydrolysis products are similar to those of fluorescein, with peak excitation and emission wavelengths of 496 and 520 nm, respectively. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy. Useful for high throughput screening applications.
Item Number 4049432
APC Number 81-6-67
Synonyms (DEVD)₂-R110, (Asp-Glu-Val-Asp)2-Rhodamine 110
Molecular Formula C₅₆H₆₆N₁₀O₂₃
Relative Molecular Mass 1247.19
CAS Registry Number [220846-75-3] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Caspase-3 substrate
Areas of Interest Apoptosis & Necrosis

M-2620

Enzyme Substrates Inhibitors
Caspase-3 (CPP-32; Yama; Apopain)