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Abz-Amyloid β/A4 Protein Precursor₇₇₀ (669-674)-EDDnp trifluoroacetate salt
Abz-Val-Lys-Met-Asp-Ala-Glu-EDDnp trifluoroacetate salt

M-2560

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2560.0001 1 mg Ships within 3-5 business days  
CHF 134.00
CHF 124.62 (7%)
M-2560.0005 5 mg Ships within 3-5 business days  
CHF 536.00
CHF 498.48 (7%)
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Details

Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It mimicks the wild-type (JMV2235) β-amyloid precursor protein (βAPP) sequence targeted by β-secretase BACE (β-site APP-cleaving activity). This FRET substrate is cleaved by BACE1, BACE2, and cathepsin D.
Item Number 4045325
Synonyms JMV2235, Abz-APP₇₇₀ (669-674)-EDDnp
Molecular Formula C₄₃H₆₂N₁₂O₁₅S
Relative Molecular Mass 1019.10
CAS Registry Number [1802078-43-8] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Alzheimer's Disease

M-2560

Enzyme Substrates Inhibitors
β-Secretase