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Availability: In stock

DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂

M-2495

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2495.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 690.00
CHF 641.70 (7%)
M-2495.0005 5 mg Ships within 3-5 business days  
CHF 2'760.00
CHF 2'566.80 (7%)
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Details

Highly soluble fluorogenic (FRET) matrix metalloproteinase (MMP) substrate with the following kcat/Km values (at pH 7.6, 37 °C): 619.000 M⁻¹s⁻¹ for MMP-2, 209.000 M⁻¹s⁻¹ for MMP-9, 40.000 M⁻¹s⁻¹ for MMP-3, and 21.000 M⁻¹s⁻¹ for MMP-1. The fluorescence increase is measured using an excitation wavelength of 340 nm and an emission wavelength of 485 nm. Due to the relatively high emission wavelength of EDANS the substrate allows convenient measurement of MMP activity in complex biological media like synovial fluid and culture medium.
Item Number 4037519
APC Number 76-4-77
Synonyms MMP Substrate III, Fluorogenic
Molecular Formula C₆₃H₈₈N₁₆O₁₄S
Relative Molecular Mass 1325.56
CAS Registry Number [193475-71-7]
Source Synthetic
Storage Conditions -20 ± 5 °C

M-2495

Enzyme Substrates Inhibitors
Matrix Metalloproteinase-1 (MMP-1)    
Matrix Metalloproteinase-2 (MMP-2)    
Matrix Metalloproteinase-3 (MMP-3)    
Matrix Metalloproteinase-9 (MMP-9)