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Availability: In stock

6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH₂ trifluoroacetate salt

M-2300

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2300.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 462.00
CHF 429.66 (7%)
M-2300.0005 5 mg Ships within 3-5 business days  
CHF 1,849.00
CHF 1,719.57 (7%)
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Details

NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH₂ (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3). This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover. It has a kcat/Km value of 2.14 x 10⁴ M⁻¹s⁻¹ and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore this compound is a suitable tool for high-throughput inhibitor screening.
Item Number 4028275
Synonyms NBD-ε-aminocaproyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMACA)-NH₂
Molecular Formula C₇₈H₁₁₁N₂₁O₁₆
Relative Molecular Mass 1598.87
CAS Registry Number [945414-97-1]
Source Synthetic
Storage Conditions -20 ± 5 °C

M-2300

Enzyme Substrates Inhibitors
Stromelysin 1    
Matrix Metalloproteinase-3 (MMP-3)