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Availability: In stock

Carbamoyl-Asp-OH · magnesium salt/Carbamoyl-Asp-OH · dipotassium salt (1:1)

M-2240

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2240.0001 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 72.00
CHF 66.96 (7%)
M-2240.0005 5 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 185.00
CHF 172.05 (7%)
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Details

Substrate for the determination of E.coli dihydroorotase (EC 3.5.2.3.), which catalyzes the cyclization of carbamoyl-Asp-OH into L-5,6-dihydroorotate. This enzyme being in the biosynthetic pathway of pyrimidine nucleotides, is an important therapeutic target for the design of new antineoplastic agents. Its activity was assayed spectrophotometrically measuring the increase of absorbance at 230 nm (ε₂₃₀ = 1170 M⁻¹cm⁻¹, Km = 0.47 mM, kcat = 143 s⁻¹).
Item Number 4027537
Molecular Formula C₁₀H₁₂K₂MgN₄O₁₀
Relative Molecular Mass 450.73
CAS Registry Number [13184-27-5] net
EINECS Number 236-134-3
Storage Conditions +5 ± 3 °C
Areas of Interest Cancer Research

M-2240

Enzyme Substrates Inhibitors
Dihydroorotase