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Availability: In stock

H-Glu-Ala-Gly-Asp-Asp-Ile-Val-Pro-Cys-Ser-Met-Ser-Tyr-Thr-Trp-Thr-Gly-Ala-OH

M-2185

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2185.0001 1 mg Ships within 1 business day  
CHF 1'040.00
CHF 967.20 (7%)
M-2185.0005 5 mg Ships within 3-5 business days  
CHF 4'161.00
CHF 3'869.73 (7%)
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Details

The peptide EAGDDIVPCSMSYTWTGA which mimics the NS5A-5B cleavage junction of the nonstructural protein (NS) is an efficient substrate used by Shimuzu et al. to detect NS3 protease activity in a standard assay (Km = 411 µM and kcat = 0.14 min⁻¹, without NS4 activator). Cleavage occurs between Cys and Ser. The cleavage products are analyzed by RP-HPLC.
Item Number 4030706
APC Number 72-3-52
One Letter Code EAGDDIVPCSMSYTWTGA
Synonyms S5A/5B
Molecular Formula C₈₁H₁₁₉N₁₉O₃₀S₂
Relative Molecular Mass 1903.08
CAS Registry Number [191529-67-6]
Source Synthetic
Storage Conditions -20 ± 5 °C
Areas of Interest Virology

M-2185

Enzyme Substrates Inhibitors
Hepatitis C Virus (HCV) NS3 Protease