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Availability: In stock

Abz-Arg-Val-Lys-Arg-Gly-Leu-Ala-m-nitro-Tyr-Asp-OH trifluoroacetate salt

M-2115

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2115.0001 1 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 196.00
CHF 182.28 (7%)
M-2115.0005 5 mg Ships within 3-5 business days  
CHF 783.00
CHF 728.19 (7%)
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Details

Internally quenched fluorogenic peptide substrate containing anthranilic acid as fluorescent donor and m-nitro-tyrosine as acceptor (quencher). The sequence Abz-RVKRGLAY(NO₂)E is based on the sequence of hemagglutinin. The FRET substrate is efficiently cleaved by furin, a subtilisin-like eukaryotic serine endoprotease with Km = 3.8 µM and kcat = 29.3 s⁻¹ (kcat/Km = 7'710'000 M⁻¹s⁻¹). Its kcat/Km value is over 2000-fold higher than that of the commonly used substrate Boc-Arg-Val-Arg-Arg-AMC (I-1645).
FRET Substrate for the basic residue-specific yeast aspartyl protease yapsin 1.
Item Number 4026550
APC Number 81-6-20
Synonyms Furin Substrate
Molecular Formula C₅₄H₈₄N₁₈O₁₆
Relative Molecular Mass 1241.37
CAS Registry Number [174838-79-0] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords Furin substrate

M-2115

Enzyme Substrates Inhibitors
Furin    
Yapsin 1