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Availability: In stock

Dnp-Pro-β-cyclohexyl-Ala-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂

M-2055

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-2055.0001 1 mg Ships within 1 business day  
CHF 268.00
CHF 249.24 (7%)
M-2055.0005 5 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 1'071.00
CHF 996.03 (7%)
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Details

Efficient fluorogenic substrate for two matrix metalloproteinases: interstitial collagenase (MMP-1) and gelatinase (MMP-9). Dnp-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-amide has favorable solubility characteristics. Both enzymes cleave this substrate between Gly and Cys(Me) (Smc), liberating a cleavage product with a fluorescence signal suitable for inhibitor screening and determining Ki values. The major advantage of this FRET substrate is its adaptability to filters commonly available on commercial plate readers (excitation at 365 nm and emission at 450 nm).
Item Number 4025472
APC Number 81-7-90
Synonyms MMP-1/MMP-9 Substrate, Fluorogenic
Molecular Formula C₄₉H₆₈N₁₄O₁₂S
Relative Molecular Mass 1077.23
CAS Registry Number [150956-92-6]
Source Synthetic
Storage Conditions -20 ± 5 °C

M-2055

Enzyme Substrates Inhibitors
Gelatinase B    
Interstitial Collagenase    
Matrix Metalloproteinase-1 (MMP-1)    
Matrix Metalloproteinase-9 (MMP-9)