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Availability: In stock

DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt

M-1940

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-1940.0001 1 mg Ships within 1 business day  
CHF 430.00
CHF 399.90 (7%)
M-1940.0005 5 mg Ships within 1 business day  
CHF 1'700.00
CHF 1'581.00 (7%)
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Details

The fluorogenic caspase-1 (ICE) substrate Dabcyl-YVADAPV-Edans is based on the principle of resonance energy transfer. It allows a continuous assay of caspase-1 that is useful in the screening of inhibitory compounds (Km = 11.4 µM, kcat = 0.79 s⁻¹). Enzymatic cleavage of the FRET substrate yields DABCYL-YVAD and APV-EDANS M-2030.
Item Number 4030475
APC Number 81-7-83
One Letter Code DABCYL- YVADAPV -EDANS
Synonyms DABCYL-YVADAPV-EDANS
Molecular Formula C₆₁H₇₆N₁₂O₁₄S
Relative Molecular Mass 1233.41
CAS Registry Number [161877-70-9] net
Source Synthetic
Storage Conditions -20 ± 5 °C
Keywords ICE FRET substrate
Areas of Interest Apoptosis & Necrosis

M-1940

Enzyme Substrates Inhibitors
Caspase-1 (ICE)