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Availability: In stock

Ac-Cys(farnesyl)-OH

M-1935

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-1935.0100 100 mg Ships within 3-5 business days  
CHF 144.00
CHF 133.92 (7%)
M-1935.0500 500 mg Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 567.00
CHF 527.31 (7%)
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Details

Substrate for S-adenosyl-methionine (SAM)-dependent methyltransferases, which methylate the C-terminal S-farnesyl-cysteine residue of several guanine nucleotidebinding proteins (G proteins) which participate in signal transduction. These include the single subunit "small" G proteins such as the p21 ras-related proteins and the heterotrimeric G proteins such as retinal transducin. Thus, a rapid assay for studying this carboxyl methyltransferase activity has been developed. Interestingly, AFC was also shown to inhibit the methylation of the transducin γ-subunit and of Ras-related proteins.
Item Number 4018082
Synonyms AFC
Molecular Formula C₂₀H₃₃NO₃S
Relative Molecular Mass 367.55
CAS Registry Number [135304-07-3]
Storage Conditions -20 ± 5 °C
Keywords Substrate for S-adenosylmethionine-dependent methyltransferase

M-1935

Enzyme Substrates Inhibitors
Protein-S-Isoprenylcysteine O-Methyltransferase