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Availability: In stock

Dnp-Pro-Leu-Gly-Cys(Me)-His-Ala-D-Arg-NH₂

M-1905

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
M-1905.0005 5 mg Ships within 3-5 business days  
CHF 258.00
CHF 239.94 (7%)
M-1905.0025 25 mg Ships within 3-5 business days  
CHF 1'030.00
CHF 957.90 (7%)
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Details

In an approach to optimize substrate specificity, two amino acids have been substituted at the cleavage site of the collagenase substrate, Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH₂ (M-1855). The substrate possesses a 10-fold better kcat/Km value for human fibroblast collagenase than the FRET substrate M-1855. However, monitoring of the enzyme activity using M-1905 requires HPLC analysis as the quencher (Trp) has been removed by the amino acid substitutions.
Item Number 4030542
APC Number 81-7-73
One Letter Code Dnp- PLGC(Me)HAr -NH₂
Synonyms MMP-1 Substrate II
Molecular Formula C₃₈H₅₇N₁₅O₁₁S
Relative Molecular Mass 932.03
CAS Registry Number [145224-98-2]
Source Synthetic
Storage Conditions -20 ± 5 °C

M-1905

Enzyme Substrates Inhibitors
Interstitial Collagenase    
Matrix Metalloproteinase-1 (MMP-1)